Monitor Carefully (one)istradefylline will improve the amount or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.enasidenib will raise the stage or influence of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Enasidenib (a weak CYP2C19 inhibitor) may well increase systemic exposure of deli